Below is a list of Health Informatics research group articles published in scientific journals together with a selection of posters presented in various international conferences. View also the list of completed bachelor, masters and doctoral thesis.

2025

Särg, D; Sirts, K; Krebs, K; Tamm, M; Metsküla, A; Oja, M; Laur, S; Vilo, J; Milani, L.

Text-based approach for detecting cases of ADEs from EHRs of participants of the Estonian Biobank

Informatics in Medicine Unlocked, 59, 2025. https://doi.org/10.1016/j.imu.2025.101701

Loo, L; Oja, M; Tamm, S; Kolde, R; Tillmann, T.

From data to prevention: early cardiovascular disease risk modeling with national health records

European Heart Journal, Vol 46, Issue Supplement_1, ehaf784.4496, 2025. DOI: 10.1093/eurheartj/ehaf784.4496

López-Güell, K; Català, M; Dedman, D; Duarte-Salles, T; Kolde, R; et al.

Clusters of post-acute COVID-19 symptoms: a latent class analysis across 9 databases and 7 countries

Journal of Clinical Epidemiology, Vol 185, 2025. DOI: 10.1016/j.jclinepi.2025.111867.

Lõo, L; Umov, N; Oja, M; Reisberg, S; Uusküla, A; Kolde, R; Tillmann, T.

Data Resource Profile: Linking electronic health and social records to study and lower health inequalities in cardiovascular diseases (BIG-HEART)

Malk, M; Mooses, K; Oja, M; Holm, J; Keidong, H; Umov, N; Tamm, S; Reisberg, S; Vilo, J; Kolde, R.

A Comprehensive Approach to Days’ Supply Estimation in a Real-World Prescription Database: Data Cleaning, Imputation, and Adherence Analysis

medRxiv 2025.09.03.25335007, 2025. DOI: 10.1101/2025.09.03.25335007

Milani, L; Alver, M; Laur, S; Reisberg, S; Haller, T; Aasmets, O; Abner, E; Alavere, H; Allik, A; Annilo, T; Fischer, K; Hofmeister, R; Hudjashov, G; Jõeloo, M; Kals, M; Karo-Astover, L; Kasela, S; Kolde, A; Krebs, K; Krigul, K L; Kronberg, J; Kruusmaa, K; Kukuškina, V; Kõiv, K; Lehto, K; Leitsalu, L; Lind, S; Luitva, L B; Läll, K; Lüll, K; Metsalu, K; Metspalu, M; Mõttus, R; Nelis, M; Nikopensius, T; Nurm, M; Nõukas, M; Oja, M; Org, E; Palover, M; Palta, P; Pankratov, V; Pantiukh, K; Pervjakova, N; Pujol-Gualdo, N; Reigo, A; Reimann, E; Smit, S; Rogozina, D; Särg, D; Taba, N; Talvik, H A; Teder-Laving, M; Tõnisson, N; Vaht, M; Vainik, U; Võsa, U; Yelmen, B; Esko, T; Kolde, R; Mägi, R; Vilo, J; Laisk, T; Metspalu, A.

The Estonian Biobank’s journey from biobanking to personalized medicine

Nat Commun 16, 3270, 2025. https://doi.org/10.1038/s41467-025-58465-3

Pineda-Moncusí, M; Rekkas, A; Martínez Pérez, Á M; Leis, A; Lopez Gomez, C L; Fey, E; Bruninx, E; Maljković, F; Sánchez-Sáez, F; Rodeiro-Boliart, J; Zsuzsa Kiss, L Z; Franz, M; Mayer, M; Eleangovan, N; Pericàs Pulido, P P; Natsiavas, P; Şen, S; Cooper, S; Reisberg, S; et al.

Changes in use and utilisation patterns of drugs with reported shortages between 2010 and 2024 in Europe and North America: a network cohort study

The Lancet Public Health, Volume 10, Issue 10, e835 – e847, 2025. DOI: 10.1016/S2468-2667(25)00194-X

Català, M; Li, X; Jödicke, A; Prats-Uribe, A; Delmestri, A; Verhamme, K; Mosseveld, M; Brash, J T; Vojinovic, D; Palomar-Cros, A; Pérez Crespo, L; Duarte-Salles, T; Oja, M; Kolde, R; Burn, E; Umuhire, D; Morales, D R.

Venous and Arterial Thromboembolic Events after COVID-19 During the Omicron Period in three European countries

Preprint.

Rajwa, P; Borkowetz, A; Abbott, T; Alberti, A; Beyer, K; Bjartell, A; Brash, J T; Chilelli, A; Davies, E; De Meulder, B; Fazekas, T; Golozar, A; Hijazy, A; Josefsson, A; Kasivisvanathan, V; Kolde, R; et al.

Observational Health Data Analysis of the Cardiovascular Adverse Events of Systemic Treatment in Patients with Metastatic Hormone-sensitive Prostate Cancer: Big Data Analytics Using the PIONEER Platform

Xie, J; Du, M; Guo, Y; Barboza, C; Brash, J T; Delmestri, A; Duarte-Salles, T; Gratton, J; Griffier, R; Kolde, R; Man, W Y; Mercadé-Besora, N; Oja, M; Seager, S; Verhamme, K; Vojinovic, D; Burn, E; Prieto-Alhambra, D; Català, M; Jödicke, A M.

Trends of prescription opioid use in Europe: A DARWIN EU® multinational cohort study including 7 European countries

Front. Pharmacol. Sec. Pharmacoepidemiology, 16, 2025, doi: 10.3389/fphar.2025.1608051

Šuvalov, H; Lepson, M; Kukk, V; Malk, M; Ilves, N; Kuulmets, H A; Kolde, R.

Using Synthetic Health Care Data to Leverage Large Language Models for Named Entity Recognition: Development and Validation Study

J Med Internet Res 2025;27:e66279. doi: 10.2196/66279

Mooses, K; Oja, M; Malk, M; Loorents, H; Pajusalu, M; Umov, N; Tamm, S; Holm, J; Keidong, H; Tillmann, T; Reisberg, S; Vilo, J; Kolde, R.

Systematic evaluation of medication adherence determinants across 137 ingredients on population-level real-world health data

medRxiv 2025.02.10.25319884. https://doi.org/10.1101/2025.02.10.25319884

Talvik, H A; Oja, M; Tamm, S; Mooses, K; Särg, D; Lõo, M; Siimon, Õ R; Šuvalov, H; Kolde, R; Vilo, J; Reisberg, S; Laur, S.
Repeatable process for extracting health data from HL7 CDA documents

Journal of Biomedical Informatics, 2025; 161. doi: https://doi.org/10.1016/j.jbi.2024.104765.

2024

Reisberg, S; Mooses, K; Kolde, R; Kõrgvee, L T; Vilo, J.

Uudne lähenemine – OMOP-andmemudelil põhinevad terviseuuringud

Eesti Arst, 2024; 103:420–429.

Pineda-Moncusí, M; Rekkas, A; Martínez Pérez, Á M; Leis, A; Lopez Gomez, C L; Fey, E; Bruninx, E; Maljković, F; Sánchez-Sáez, F; Rodeiro, J; Zsuzsa Kiss, L Z; Franz, M; Mayer, M; Eleangovan, N; Pulido Pau, P P; Natsiavas, P; Şen, S; Cooper, S; Reisberg, S; et al.

Trends of use of drugs with suggested shortages and their alternatives across 52 real world data sources and 18 countries in Europe and North America

Pajusalu, M; Mooses, K; Oja, M; Tamm, S; Haug, M; Kolde, R.

TrajectoryViz: Interactive visualization of treatment trajectories

Informatics in Medicine Unlocked. 2024; 49. doi: https://doi.org/10.1016/j.imu.2024.101558

Rajwa, P; Borkowetz, A; Abbott, T; Alberti, A; Bjartell, A; Brash, J T; Campi, R; Chilelli, A; Conover, M; Constantinovici, N; Davies, E; De Meulder, B; Eid, S; Gacci, M; Golozar, A; Hafeez, H; Haque, S; Hijazy, A; Hulsen, T; Josefsson, A; Khalid, S; Kolde, R; Kotik, D; Kurki, S; Lambrecht, M; Leung, C H; Moreno, J; Nicoletti, R; Nieboer, D; Oja, M; Palanisamy, S; Prinsen, P; Reich, C; Resta, G R; Ribal, M J; Rivas, J G; Smith, E; Snijder, R; Steinbeisser, C; Vandenberghe, F; Cornford, P; Evans-Axelsson, S; N’Dow, J; Willemse, P P M.

Research Protocol for an Observational Health Data Analysis on the Adverse Events of Systemic Treatment in Patients with Metastatic Hormone-sensitive Prostate Cancer: Big Data Analytics Using the PIONEER Platform

European Urology Open Science. 2024; 63:81-88. DOI: 10.1016/j.euros.2024.02.019

Alver, M; Kaselaa, S; Haring, L; Luitva, L B; Estonian Biobank Research Team; Health Informatics Research Team; Fischer, K; Möls, M; Milani, L.

Genetic predisposition and antipsychotic treatment effect on metabolic syndrome in schizophrenia: a ten-year follow-up study using the Estonian Biobank

The Lancet Regional Health – Europe, Vol 41, 100914, 2024. DOI: DOI: 10.1016/j.lanepe.2024.100914

Mooses, K; Šavrova, A; Pajusalu, M; Oja, M; Tamm, S; Haug, M; Padrik, L; Laanpere, M; Uusküla, A; Kolde, R.

Using electronic health records to evaluate the adherence to cervical cancer prevention guidelines: A cross-sectional study

Preventive Medicine, 183, 2024. DOI: 10.1016/j.ypmed.2024.107982

Burkard, T; López-Güell, K; Gorbachev, A; Bellas, L; Jödicke, A M; Burn, E; de Ridder, M; Mosseveld, M; Gratton, J; Seager, S; Vojinovic, D; Mayer, M A; Ramírez-Anguita, J M; Machín, A L; Oja, M; Kolde, R; Bonadt, K; Prieto-Alhambra, D; Reich, C; Català, M.

Calculating daily dose in the Observational Medical Outcomes Partnership Common Data Model.

Pharmacoepidemiol Drug Safety. 2024; 33(6):e5809. DOI:10.1002/pds.5809

Xie, J; López-Güell, K; Dedman, D; Duarte-Salles, T; Kolde, R; et al.

Incidence of post-acute COVID-19 symptoms across healthcare settings in seven countries: an international retrospective cohort study using routinely-collected data

eClinicalMedicine, Volume 77, 102903, 2024. DOI: DOI: 10.1016/j.eclinm.2024.102903

Haug, M; Oja, M; Pajusalu, M; Mooses, K; Reisberg, S; Vilo, J; Giménez, A F; Falconer, T; Danilović, A; Maljkovic, F; Dawoud, D; Kolde, R.

Markov modeling for cost-effectiveness using federated health data network

Journal of the American Medical Informatics Association, 2024; ocae044, DOI: 10.1093/jamia/ocae044

Uusküla, A; Oja, M; Tamm, S; Tisler, A; Laanpere, M; Padrik, L; Nygard, M; Reisberg, S; Vilo, J; Kolde, R.

Vaktsineerimiseelne tüübispetsiifiline inimese papilloomiviiruse levimus emakakaela tsütoloogilise uuringuleiu raskusastme järgi Eestis.

Eesti Arst, 2024. 103(2):100

Markus, A F; Rijnbeek, P R; Kors, J A; Burn, E; Duarte-Salles, T; Haug, M; Kim, C; Kolde, R; Lee, Y; Park, H S; Park, R W; Prieto-Alhambra, D; Reyes, C; Krishnan, J A; Brusselle, G G; Verhamme, K M C.

Real-world treatment trajectories of adults with newly diagnosed asthma or COPD

Mercadé-Besora, N; Li, X; Kolde, R; Trinh, N T H; Sanchez-Santos, M T; Man, W Y; Roel, E; Reyes, C; Delmestri, A; Nordeng, H M E; Uusküla, A; Duarte-Salles, T; Prats, C; Prieto-Alhambra, D; Jödicke, A M; Català, M.

The role of COVID-19 vaccines in preventing post-COVID- 19 thromboembolic and cardiovascular complications

Heart 2024;0:1–9. DOI:10.1136/heartjnl-2023-323483

2023

Oja, M; Tamm, S; Mooses, K; Pajusalu, M; Talvik, H A; Ott, A; Laht, M; Malk, M; Lõo, M; Holm, J; Haug, M; Šuvalov, H; Särg, D; Vilo, J; Laur, S; Kolde, R; Reisberg, S.

Transforming Estonian health data to the Observational Medical Outcomes Partnership (OMOP) Common Data Model: lessons learned

JAMIA Open, 2023: 6 (4). DOI: 10.1093/jamiaopen/ooad100

Uusküla, A; Oja, M; Tamm, S; Tisler, A; Laanpere, M; Padrik, L; Nygard, M; Reisberg, S; Vilo, J; Kolde, R.

Prevaccination Prevalence of Type-Specific Human Papillomavirus Infection by Grade of Cervical Cytology in Estonia

JAMA Network Open, 2023:6 (2), e2254075. DOI: 10.1001/jamanetworkopen.2022.54075

Media coverage (in Estonian)

Short overview in Estonian in Journal Eesti Arst.

Leitsalu, L; Reigo, A; Palover, M; Nikopensius, T; Läll, K; Krebs, K; Reisberg, S; Mägi, R; Kals, M; Alavere, H; Nõukas, M; Kolk, A; Normet, I; Tammesoo, M.L; Käärik, E; Puusepp, M; Metsalu, K; Allik, A; Milani, L; Fischer, K; Tõnisson, N; Metspalu, A.

Lessons learned during the process of reporting individual genomic results to participants of a population-based biobank

Eur J Hum Genet 31, 1048–1056, 2023. DOI: 10.1038/s41431-022-01196-6

Kurvits, S; Harro, A; Reigo, A; Ott, A; Laur, S; Särg, D; Tampuu, A; Alasoo, K; Vilo, J; Milani, L; Haller, T.

Common clinical blood and urine biomarkers for ischemic stroke: an Estonian Electronic Health Records database study.

Eur J Med Res 28, 133, 2023. DOI:10.1186/s40001-023-01087-6

Mooses K; Vesilind, K; Oja M; Tamm S; Haug M; Kalda R; Suija K, Tisler A, Meister T; Malk M, Uusküla A; Kolde R.

The use of prescription drugs and health care services during the 6‑month post‑COVID‑19 period

Scientific Reports, 2023:13, 11638100394. DOI: 10.1038/s41598-023-38691-9.

Gandaglia, G; Pellegrino, F; Golozar, A; De Meulder, B; Abbott, T; Achtman, A; Omar, M.I; Alshammari, T; Areia, C; Asiimwe, A; Beyer, K; Bjartell, A; Campi, R; Cornford, P; Falconer, T; Feng, Q; Gong, M; Herrera, R; Hughes, N; Hulsen, T; Kinnaird, A; Lai, L.Y.H; Maresca, G; Mottet, N; Oja, M; et al. 

Clinical Characterization of Patients Diagnosed with Prostate Cancer and Undergoing Conservative Management: A PIONEER Analysis Based on Big Data

European Urology, 2023. DOI: 10.1016/j.eururo.2023.06.012

Jürisson, M; Milani, L; Saar, A; Pajusalu, S; Kalda, R; Fischer, K; Vilo, J; Starkopf, J; Solvak, M; Kaarna, K; Kingo, K; Metspalu, M.

Personaalmeditsiini keskuse loomisest Eestis

Eesti Arst, 2023. 

Haug, M; Kolde, R; Oja, M; Pajusalu, M.

Modeling Patient Treatment Trajectories Using Markov Chains for Cost Analysis

Stud Health Technol Inform. 302:755-756, 2023. DOI: doi:10.3233/SHTI230258

Voss, E.A; Shoaibi, A; Lai, L.Y.H; Blacketer, C; Alshammari, T; Makadia, R; Haynes, K; Sena, A.G; Rao, G; van Sandijk, S; Fraboulet, C; Boyer, L; Le Carrour, T; Horban, S; Morales, D.R; Roldán, J.M; Ramírez-Anguita, J.M; Mayer, A; de Wilde, M; John, L.H; Duarte-Salles, T; Roel, E; Pistillo, A; Kolde, R; et al.

Contextualising adverse events of special interest to characterise the baseline incidence rates in 24 million patients with COVID-19 across 26 databases: a multinational retrospective cohort study

eClinicalMedicine. Part of THE LANCET Discovery Science, 2023:58. DOI: 10.1016/j.eclinm.2023.101932

Rosenberg, M; Thetloff, M; Tamm, S; Kuusk, K; Reisberg, S; Vilo, J.

Kroonilise neeruhaiguse levimus Eesti e-tervise andmete alusel

2022

Meister, T; Pisarev, H; Kolde, R; Kalda, R; Suija, K; Milani, L; Karo-Astover, L; Piirsoo, M; Uusküla, A.

Clinical characteristics and risk factors for COVID-19 infection and disease severity: A nationwide observational study in Estonia

PLoS ONE, 2022:17, e0270192. DOI: 10.1371/journal.pone.0270192

Uusküla, A; Kalda, R; Solvak, M; Jürisson, M; Käärik, M; Fischer, K; Keis, A; Raudvere, U; Vilo, J; Peterson, H; Käärik, E; Metspalu, M; Jürgenson, T; Milani, L; Kolberg, L; Tiit, E.M; Vassil, K.

The 1st year of the COVID-19 epidemic in Estonia: a population-based nationwide sequential/consecutive cross-sectional study

Public Health, Vol 205, pages 150-156, 2022. DOI: 10.1016/j.puhe.2022.02.004

Uusküla, A; Jürgenson T; Pisarev H; Kolde, R; Meister, T; Tisler, A; Suija, K; Kalda, R; Piirsoo, M; Fischer K.

Long-term mortality following COVID-19 infection: a national cohort study from Estonia

The Lancet Regional Health – Europe, 2022:100394. DOI: 10.1016/j.lanepe.2022.100394.

Gomez Rivas, J; Lai, L.Y.H; Chatzichristos, C; Van Hemelrijck, M; Beyer, K; Oja, M; Tamm, S; Reisberg, S; Vilo, J; Asiimwe, A; Steinbeisser, C; Bjartell, A; Sakalis, V; N’Dow, J.

Baseline characteristics and outcomes of 10.485 prostate cancer patients on delayed palliative management: A report from PIONEER, a big data for better outcome programme

European Urology, vol 81, pages S1551-S1552, 2022. DOI: 10.1016/S0302-2838(22)01130-7

Lepamets, M; Auwerx, C; Nõukas, M; Claringbould, A; Porcu, E; Kals, M; Jürgenson, T; Morris, A.P; Võsa, U; Bochud, M; Stringhini, S; Wijmenga, C; Franke, L; Peterson, H; Vilo, J; Lepik, K; Mägi, R; Kutalik, Z.

Omics-informed CNV calls reduce false-positive rates and improve power for CNV-trait associations

Human Genetics and Genomics Advances, Volume 3, Issue 4, 100133. 2022. DOI: 10.1016/j.xhgg.2022.100133

Yang, C; Williams, Ross D; Swerdel, JN; Almeida, JR; Brouwer, ES.; Burn, E; Carmona, L; Chatzidionysiou, K; Duarte-Salles, T; Fakhouri, W; Hottgenroth, A; Jani, M; Kolde, R; Kors, JA; Kullamaa, L; Lane, J; Marinier, K; Michel, A; Stewart, HM; Prats-Uribe, A … Rijnbeek, PR. 

Development and external validation of prediction models for adverse health outcomes in rheumatoid arthritis: A multinational real-world cohort analysis

Seminars in Arthritis and Rheumatism, 2022:56, 152050. DOI: 10.1016/j.semarthrit.2022.152050

Künnapuu, K; Ioannou, S; Ligi, K; Kolde, R; Laur, S; Vilo, J; Rijnbeek, PR; Reisberg, S.

Trajectories: a framework for detecting temporal clinical event sequences from health data standardized to the Observational Medical Outcomes Partnership (OMOP) Common Data Model

JAMIA Open, 2022:5 (1), 1−11. DOI: 10.1093/jamiaopen/ooac021

2021

Ostrak, A; Randmets, J; Sokk, V; Laur, S; Kamm, L.

Implementing Privacy-Preserving Genotype Analysis with Consideration for Population Stratification

Cryptography, 2021:5 (3), ARTN 21. DOI: 10.3390/cryptography5030021.

2020

Laur, S; Orasmaa, S; Särg, D; Tammo, P.

EstNLTK 1.6: Remastered Estonian NLP Pipeline. Proceedings of the 12th Language Resources and Evaluation

Conference: International Conference on Language Resources and Evaluation (LREC), Marseille, France, 2020. European Language Resources Association, 7152−7160.

Krebs, K; Bovijn, J; Zheng, N; Lepamets, M; Censin, JC; Jürgenson, T; Särg, D; Abner, E; Laisk, T; Luo, Y; Skotte, L; Geller, F; Feenstra, B; Wang, W; Auton, A;  Raychaudhuri, S; Esko, T; Metspalu, A; Laur, S… Fadista, J.

Genome-wide Study Identifies Association between HLA-B∗55:01 and Self-Reported Penicillin Allergy

The American Journal of Human Genetics, 2020:107 (4), 612−621. DOI: 10.1016/j.ajhg.2020.08.008.

2019

James, G; Reisberg, S; Lepik, K; Galwey, N; Avillach, P; Kolberg, L; Mägi, R; Esko, T; Alexander, M; Waterworth, D; Loomis, AK; Vilo, J.

An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank

PLoS ONE, 2019:14 (4), ARTN e0215026. DOI: 10.1371/journal.pone.0215026.

Ward, DV; Hoss, AG; Kolde, R; van Aggelen, HC; Loving, J; Smith, SA; Mack, DA; Kathirvel, R; Halperin, JA; Buell, DJ; Wong, BE; Ashworth, JL; Fortunato-Habib, MM; Xu, L; Barton, BA; Lazar, P; Carmona, JJ; Mathew, J; Salgo, IS; Gross, BD … Ellison, RT, III.

Integration of genomic and clinical data augments surveillance of healthcare-acquired infections

Infection Control and Hospital Epidemiology, 2019:40 (6), 649−655. DOI: 10.1017/ice.2019.7

Reisberg, S; Galwey, N; Avillach, P; Sahlqvist, A.S; Kolberg, L; Mägi, R; Esko, T; Vilo, J; James, G.

Comparison of variation in frequency for SNPs associated with asthma or liver disease between Estonia, HapMap populations and the 1000 genome project populations

International Journal of Immunogenetics, 46, 2, 49-58, 2019. DOI: 10.1111/iji.12413

Palover, M; Leitsalu, L; Krebs, K; Lall, K; Kals, M; Nikopensius, T; Reigo, A; Milani, L; Fischer, K; Magi, R; Allik, A; Kolk, B; Metsalu, K; Puusepp, M; Mikkel, K; Tammesoo, M; Pintsaar, E; Temberg, T; Reisberg, S; Vilo, J … Metspalu, A.

Reporting genetic risks to participants of the Estonian Biobank, Genome Center

European Journal of Human Genetics, 2019:27 (1), 544−545

Tasa T, Krebs K, Kals M, Mägi R, Lauschke VM, Haller T, Puurand T, Remm M, Esko T, Metspalu A, Vilo J, Milani L.

Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records

European Journal of Human Genetics, vol 27, 2, 442-454, 2019. DOI: 10.1038/s41431-018-0300-6

Reisberg, S; Krebs, K; Lepamets, M; Kals, M; Mägi, R; Metsalu, K; Lauschke, VM; Vilo, J; Milani, L.

Translating genotype data of 44,000 biobank participants into clinical pharmacogenetic recommendations: challenges and solutions

Genetics in Medicine, 2019 DOI: 10.1038/s41436-018-0337-5

2018

Tasa, T; Kalamees, R; Vilo, J; Lutsar, I; Metsvaht, T.

External evaluation of population pharmacokinetic models for vancomycin in neonates

Krebs, K; Tasa, T; Kals, M; Magi, R; Esko, T; Metspalu, A; Vilo, J; Milani, L.

Genetic variation in the Estonian population: a pharmacogenomic study of adverse drug reactions using electronic health records

European Journal of Human Genetics volume 27, pages 442–454, 2019. DOI: 10.1038/s41431-018-0300-6

Mooses, K; Oja, M; Reisberg, S; Vilo, J; Kull, M.

Validating Fitbit Zip for monitoring physical activity of children in school: a cross-sectional study

BMC Public Health, 2018:18. DOI: 10.1186/s12889-018-5752-7.

Bogdanov, D; Kamm, L; Laur, S; Sokk, V.

Implementation and Evaluation of an Algorithm for Cryptographically Private Principal Component Analysis on Genomic Data

IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2018:15 (5), 1427−1432. DOI: 10.1109/TCBB.2018.2858818.

Sadama, H; Pihlaka, A; Kivila, A; Pihelgas, S; Jaago, M; Adler, P; Vilo, J; Vapalahti, O; Neuman, T; Lindholm, D; Partinen, M; Vaheri, A; Palm, K.

Prostaglandin D2 Receptor DP1 Antibodies Predict Vaccine-induced and Spontaneous Narcolepsy Type 1: Large-scale Study of Antibody Profiling

eBioMedicine, Volume 29, 47 – 59, 2018. DOI: 10.1016/j.ebiom.2018.01.043.

Bogdanov, D; Kamm, L; Laur, S; Sokk, V.

Rmind: A Tool for Cryptographically Secure Statistical Analysis

IEEE Transactions on Dependable and Secure Computing, 2018:15 (3), 481−495. DOI: 10.1109/TDSC.2016.2587623

2017

Modhukur, V; Iljasenko, T; Metsalu, T; Lokk, K; Laisk-Podar, T; Vilo, J.

MethSurv: a web tool to perform multivariable survival analysis using DNA methylation data

Epigenomics, 10(3), 277–288, 2017. DOI:10.2217/epi-2017-0118

Fishman, D; Kisand, K; Hertel, C; Rothe, M; Remm, A; Pihlap, M; Adler, P; Vilo, J; Peet, A; Meloni, A; Podkrajsek, K; Battelino, T; Bruserud, Ø; Wolff, A; Husebye, E; Kluger, N; Krohn, K; Ranki, A; Peterson, H; Hayday, A; Peterson, P.

Autoantibody Repertoire in APECED Patients Targets Two Distinct Subgroups of Proteins

Frontiers in Immunology, Vol 8, 2017. DOI: 10.3389/fimmu.2017.00976

Tasa, T; Metsvaht, T; Kalamees, R; Vilo, J; Lutsar, I.

DosOpt: a tool for personalized Bayesian dose adjustment of vancomycin in neonates

Therapeutic Drug Monitoring, 39, 6, 604-613, 2017. DOI: 10.1097/FTD.0000000000000456

Kukushkina, V; Modhukur, V; Suhorutšenko, M; Peters, M; Mägi, R; Rahmioglu, N; Velthut-Meikas, A; Altmäe, S; Esteban, F; Vilo, J; Zondervan, K; Salumets, A; Laisk-Podar, T.

DNA methylation changes in endometrium and correlation with gene expression during the transition from pre-receptive to receptive phase

Sci Rep 7, 3916, 2017. DOI: 10.1038/s41598-017-03682-0

Reisberg, S; Iljasenko, T; Läll, K; Fischer, K; Vilo, J.

Comparing distributions of polygenic risk scores of type 2 diabetes and coronary heart disease within different populations

PLoS ONE, 2+17:12 (7), e0179238−e0179238. DOI: 10.1371/journal.pone.0179238.

Muromägi, A; Sirts, K; Laur, S.

Linear Ensembles of Word Embedding Models

Proceedings of the 21st Nordic Conference on Computational Linguistics: NoDaLiDa, Gothenburg, Sweden, 22.-24.05.2017. Linköping University Electronic Press, 96−104.

2016

Reimand J; Arak T; Adler P; Kolberg L; Reisberg S; Peterson H; Vilo J.

g:Profiler-a web server for functional interpretation of gene lists (2016 update)

Nucleic Acids Research, 2016, gkw199. DOI: 10.1093/nar/gkw199

Roberto, G; Leal, I; Sattar, N; Loomis, AK; Avillach, P; Egger, P; van Wijngaarden, R; Ansell, D; Reisberg, S; Tammesoo, ML; Alavere, H; Pasqua, A; Pedersen, L; Cunningham, J; Tramontan, L; Mayer, MA; Herings, R; Coloma, P; Lapi, F; Sturkenboom, M … Gini, R. 

Identifying Cases of Type 2 Diabetes in Heterogeneous Data Sources: Strategy from the EMIF Project

PLoS ONE, 2016:11 (8), e0160648. DOI: 10.1371/journal.pone.0160648.

Orasmaa, S; Petmanson, T; Tkatšenko, A; Laur, S; Kaalep, HJ.

EstNLTK – NLP Toolkit for Estonian

Proceedings of the Tenth International Conference on Language Resources and Evaluation (LREC 2016): The International Conference on Language Resources and Evaluation; Portorož, Slovenia. 2460−2466.

Kolde, R; Märtens, K; Lokk, K; Laur, S; Vilo, J.

seqlm: an MDL based method for identifying differentially methylated regions in high density methylation array data

Bioinformatics, 2016, btw304. DOI: 10.1093/bioinformatics/btw304.

2015

Peterson, P; Tserel, L; Kolde, R; Limbach, M; Tretyakov, K; Kasela, S; Kisand, K; Saare, M; Vilo, J; Metspalu, A; Milani, L.

Age-related profiling of DNA methylation in CD8+ T cells reveals changes in immune response and transcriptional regulator genes

Sci Rep 5, 13107, 2016. DOI: 10.1038/srep13107

Kolde, R; Vilo, J.

GOsummaries: an R Package for Visual Functional Annotation of Experimental Data

F1000Res. 4:574, 2015. DOI: 10.12688/f1000research.6925.1

Metsalu, T; Vilo, J.

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

Nucleic Acids Research, Vol 43, Issue W1, pages W566–W570, 2015. DOI: 10.1093/nar/gkv468

Örd, T; Örd, D; Adler, P; Vilo, J; Örd, T.

TRIB3 enhances cell viability during glucose deprivation in HEK293-derived cells by upregulating IGFBP2, a novel nutrient deficiency survival factor

Molecular Cell Research,
Vol 1853, Issue 10, Part A, ages 2492-2505, 2015. DOI: 10.1016/j.bbamcr.2015.06.006.

2014

Bogdanov, D; Kamm, L; Laur, S; Pruulmann-Vengerfeldt, P; Talviste, R; Willemson, J.

Privacy-preserving statistical data analysis on federated databases

Privacy Technologies and Policy: Annual Privacy Forum 2014, 20.-21. mai 2014, Ateena, Kreeka.  DOI: 10.1007/978-3-319-06749-0_3.

2013

Reisberg, S; Sirel, R; Kalda, R; Merzin, M; Pruulmann, J; Vilo, J.

Elektrooniliste terviselugude analüüsimise võimalused Tartu perearstide infosüsteemi näitel

Eesti Arst, 2013:92 (8), 452−459.

Kamm, L; Bogdanov, D; Laur, S; Vilo, J.

A new way to protect privacy in large-scale genome-wide association studies

Bioinformatics, 2013:29 (7), 886−893. DOI: 10.1093/bioinformatics/btt066.

Tkachenko, A; Petmanson, T; Laur, S.

Named Entity Recognition in Estonian

Proceedings of the 4th Biennial International Workshop on Balto-Slavic Natural Language Processing, Sofia, Bulgaria, 8-9 August 2013.  ACL: Omnipress, 78−83.

2012

Altmäe, S; Reimand, J; Hovatta, O; Zhang, P; Kere, J; Laisk, T; Saare, M; Peters, M; Vilo, J; Stavreus-Evers, A; Salumets, A.

Research resource: interactome of human embryo implantation: identification of gene expression pathways, regulation, and integrated regulatory networks

Molecular Endocrinology, Vol 26, Issue 1, pages 203–217, 2012. DOI: 10.1210/me.2011-1196

Krug, A.K; Kolde, R; Gaspar, J.A; Rempel, E; Balmer, N.V; Meganathan, K; Vojnits, K; Baquié, M; Waldmann, T; Ensenat-Waser, R; Jagtap, S; Evans, R.M; Julien, S; Peterson, H; Zagoura, D; Kadereit, S; Gerhard, D; Sotiriadou, I; Heke, M; Natarajan, K; Henry, M; Winkler, J; Marchan, R; Stoppini, L; Bosgra, S; Westerhout, J; Verwei, M; Vilo, J; et al.

Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach

Arch Toxicol 87, 123–143, 2013. DOI: 10.1007/s00204-012-0967-3

Bogdanov, D; Jagomägis, R; Laur, S.

A universal toolkit for cryptographically secure privacy-preserving data mining

In:  Proceedings of the Pacific Asia Workshop on Intelligence and Security Informatics 2012 (112−126). 

Kolde, R; Laur, S; Adler, P; Vilo, J.

Robust Rank Aggregation for gene list integration and meta-analysis

Bioinformatics, 2012:28 (4), 573−580. DOI: 10.1093/bioinformatics/btr709

2011

Tretyakov, K.; Laur, S.; Vilo, J.

G = MAT: Linking Transcription Factor Expression and DNA Binding Data

PLoS ONE, 2011:6 (1), e14559. DOI: 10.1371/journal.pone.0014559.

Ilmjärv, S; Luuk, H; Laur, S; Vasar, E; Vilo, J.

Non-parametric probe-level estimation of differential expression

In: . 19th Annual International Conference on Intelligent Systems for Molecular Biology and 10th European Conference on Computational Biology, Vienna (Austria), 2011.

2008

Jänes, J; Laur, S; Kolka, I.

Detection and characterisation of Hα emission lines from Gaia BP/RP spectra

C.A.L. Bailer-Jones. Classification and discovery in large astronomical surveys (71−75).  Melville, New York: AIP.

Bogdanov, D; Laur, S; Willemson, J.

Sharemind: a framework for fast privacy-preserving computations

Computer Security – ESORICS 2008: 13th European Symposium on Research in Computer Security Málaga, Spain, 192−206.  DOI: 10.1007/978-3-540-88313-5_13.

2006

Laur, S; Lipmaa, H; Mielikäinen, T

Cryptographically Private Support Vector Machines

KDD-2006: The Twelfth ACM SIGKDD International Conference on Knowledge Discovery and Data Mining, Philadelphia, USA, 2006, 618−624.

2005

Lipmaa, H; Mielikäinen, T; Laur, S

Private Itemset Support Counting

Seventh International Conference on Information and Communications Security, ICICS ’05, 2005:97−111.